This video, presented by Quinn Stillson MD, explores five key supplements identified as geroprotective agents—compounds that target the root causes of aging at a molecular and cellular level to potentially extend lifespan and healthspan (0:00 - 1:03).
The Top 5 Lifespan Extension Supplements:
- Taurine (1:04 - 12:38): An amino acid that helps decrease five hallmarks of aging, particularly mitochondrial dysfunction. The suggested dose is 3 grams per day, preferably split throughout the day to maximize absorption (9:24 - 12:38).
- Spermidine (12:39 - 23:01): A polyamine that supports autophagy (cellular cleanup). A plant-based extract (wheat or rice germ) is recommended, with a suggested intake of 3.3 to 10 milligrams per day (17:44 - 23:01).
- Green Tea Extract (EGCG) (23:02 - 34:15): Known for enhancing mitochondrial resilience. The doctor recommends a mixture (approximately 50% EGCG) with a target of about 300 milligrams of EGCG daily to remain within a safe threshold, ideally taken between meals (27:41 - 34:15).
- Astaxanthin (34:16 - 41:37): A potent antioxidant that targets six hallmarks of aging. Because it is highly fat-soluble, it should be taken with fat-containing meals. The recommended dose ranges from 12 to 24 milligrams per day (37:34 - 41:37).
- Glycine (+ NAC) (41:38 - 52:38): Acts by mimicking methionine restriction and boosting glutathione levels. The recommended protocol is 6-7 grams of glycine and 3 grams of NAC per day, split into multiple doses (46:41 - 52:38).
Medical Disclaimer: This video is for educational purposes and does not constitute medical advice. Consult with a licensed healthcare provider before starting any new supplement regimen.
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